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Text File  |  1987-10-07  |  542b  |  16 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, ACEBUTOLOL DOSAGE
  3.          SHOULD BE CAREFULLY ADJUSTED TO AVOID TOXICITY (PROLONGED
  4.          HYPOTENSION, BRADYCARDIA).
  5.  
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE ADJUSTED
  7.          BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.  
  9.                      CREATININE
  10.                       CLEARANCE             DOSAGE
  11.                      (ML/MINUTE)
  12.  
  13.                         10-50          50% of normal
  14.                          <10           30 to 50% of normal
  15.  
  16.